F. Asensi et al., RISK BENEFIT IN THE TREATMENT OF CHILDREN WITH IMIPENEM-CILASTATIN FOR MENINGITIS CAUSED BY PENICILLIN-RESISTANT PNEUMOCOCCUS, Journal of chemotherapy, 5(2), 1993, pp. 133-134
A new case of pneumococcal meningitis in a child successfully treated
with imipenem-cilastatin after failure of standard antibiotics is pres
ented. Seizures, as the major adverse effect, were easily treated and
no sequelae were later observed. The difficulty in distinguishing betw
een seizures due to meningitis and those due to imipenem is discussed.
We conclude that imipenem-cilastatin is a good alternative therapy in
children's meningitis caused by pneumococcus resistant to standard an
tibiotics.