EXTRAORDINARY CLINICAL AND MORPHOLOGICAL FEATURES OF AN ENDOCRINE ACTIVE GLOMUS TUMOR (PARAGANGLIOMA)

A glomus jugulare tumor arises from the glomus bodies located in the a dventitia of the dome of the jugular bulb. A glomus tumor has the same microscopic appearance as a carotid body tumor. The present report in cludes the extraordinary clinical and morphological features of a cate cholamin-secreting glomus tumor (paraganglioma) in a 41-year-old woman . The patient presented with uncontrollable hypertension und pulsatile tinnitus. The diagnostic and therapeutic management is reported, incl uding MIBG scintigraphy, computed tomography, magnetic resonance imagi ng, embolization, angiography, selective venous sampling studies and c ontrol of hypertension. After cardiovascular stabilization and tumor e mbolization, the tumor was removed surgically, with subsequent resolut ion of hypertension. While light microscopical analysis showed a class ical glomus tumor, ultrastructural analysis revealed particular detail s of the tumor cells.