O. Nelzen et al., HIGH PREVALENCE OF DIABETES IN CHRONIC LEG ULCER PATIENTS - A CROSS-SECTIONAL POPULATION STUDY, Diabetic medicine, 10(4), 1993, pp. 345-350
Citations number
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Categorie Soggetti
Endocrynology & Metabolism","Medicine, General & Internal
In a cross-sectional survey, designed to detect all patients with curr
ent chronic leg ulcers, 27 % of the patients had diabetes mellitus. Th
e outcome for the 104 examined diabetic patients has been evaluated an
d compared with the 278 nondiabetic patients. The purpose was to estab
lish the prevalence of leg ulcers among diabetic patients and to asses
s potential causes. The point prevalence was calculated by extrapolati
ng the leg ulcer frequency to the total diabetic population in the stu
died area. The point prevalence for active leg ulcers (including foot
ulcers) in diabetic patients was 3.5 % (95 % Cl 2.8-4.2). Ulcers above
the malleoli were almost as common as foot ulcers. Peripheral vascula
r disease was present in 67 % of all ulcerated legs in patients with d
iabetes compared to 42 % in nondiabetic patients (p < 0.001). In 72 %
of foot ulcers in diabetic patients arterial impairment was judged to
be a contributing aetiological factor and in nondiabetic patients 45 %
(p < 0.001). Ulcers solely attributed to possible neuropathy were les
s common (15 %). Ulcers with multifactorial causes were common above t
he malleoli. This survey has given the size of the problem and indicat
es macroangiopathy to be the dominating factor responsible for slow or
nonhealing ulcers in diabetic patients. Objective assessment of arter
ial circulation is mandatory and signs of arterial impairment require
consultation with a vascular surgeon.