Y. Francois et al., OUTCOME OF PERIANAL FISTULAS IN CROHNS-DISEASE - VALUE OF HUGHES PATHOGENIC CLASSIFICATION, International journal of colorectal disease, 8(1), 1993, pp. 39-41
Applying the Hughes' pathogenic classification of anoperineal lesions
of Crohn's disease, this study was conducted to find out its possible
prognostic value in perianal fistulas. Thirty-eight patients with ano-
perianal fistulas were included; primary specific lesions (condyloma,
cavitating ulcer, fissure) were found in 22 patients (group 1) and wer
e absent in the other 16 patients (group 2). Patients of group 1 under
went more abdominal surgical interventions (G 1: 68 %; G 2: 31 % - P =
0.05), as well as proctological interventions (G 1: 2.95 operations/p
atient vs 1.35 in G 2 - P = 0.01). Perfect continence was recorded ult
imately in 31.8 % patients of G 1 compared to 62.5 % of G 2. This stud
y shows the very poor prognosis of ano-perianal fistulas in Crohn's di
sease.