In 1990, approximately 1500 of Glasgow's estimated 9400 injecting drug
users attended the city's four needle and syringe exchanges. In the s
ame year, a multisite and citywide strategy was used to interview an e
stimated 5% sample of the city's injectors using an internationally ag
reed WHO structured schedule. Of the 503 injectors who participated in
the study 54% (n = 272) had made use of exchanges in the last 6 month
s (including 165 injectors recruited from exchanges), while the remain
ing 46% (n = 231) had not. Twenty-seven variables were entered into a
stepwise discriminant analysis to predict group membership (attenders
vs. non-attenders). Fourteen variables emerged in the final discrimina
nt function, which explained 17.3% of the variance between the two gro
ups. Comparison of the model to random classification of cases resulte
d in a third fewer cases being wrongly assigned. Needle exchange atten
ders report injecting fewer drugs, less injecting with and passing on
of used equipment and greater use of condoms with casual partners, com
pared to non-attenders. They also had greater knowledge of AIDS and ha
d made and maintained more harm reduction changes, although they were
less likely to have received treatment than non-attenders. The finding
that attenders were less likely to inject with or pass on used needle
s and syringes is discussed in the context of availability of clean eq
uipment and perception of risk. Variables reflecting lifestyle such as
housing, employment and prison experience were not found to have any
discriminatory power.