MORPHOLOGY OF TISSUE DESTRUCTION INDUCED BY FOCUSED ULTRASOUND

Authors
SUSANI M MADERSBACHER S KRATZIK C VINGERS L MARBERGER M
Citation
M. Susani et al., MORPHOLOGY OF TISSUE DESTRUCTION INDUCED BY FOCUSED ULTRASOUND, European urology, 23, 1993, pp. 34-38
Citations number
10
Categorie Soggetti
Urology & Nephrology
Journal title
European urology → ACNP
ISSN journal
03022838
Volume
23
Year of publication
1993
Supplement
1
Pages
34 - 38
Database
ISI
SICI code
0302-2838(1993)23:<34:MOTDIB>2.0.ZU;2-W
Abstract
The effect of high-intensity focused ultrasound (HIFU) ablation on the morphology of prostatic, renal and testicular tissue was studied by l ight and electron microscopy. Specimens were obtained in 21 patients 1 h to 10 weeks after lesioning. Histological findings showed consisten t coagulative necrosis with precisely defined, sharp margins to normal tissue. Lesion size and position correlated well with the assumed tar get zones, suggesting that HIFU permits therapeutic tissue ablation.