A system generating focused elastic ultrashort waves has been develope
d wit the aim to destroy tumors by an extracorporeal way. Experimental
studies on different targets (plastic phantoms, organ samples and nor
mal live tissues in pigs) have been done showing the good focusing of
the device and the possibility of getting a focal tissular coagulative
necrosis. Studies on cultured tumor cells and implanted tumors in rat
s have shown a local effect on cells or tumor growth with the absence
of metastatic risks. First human trials are summarized. This technique
we call focused extracorporeal pyrotherapy could be useful for the tr
eatment of cancers.