Vertebral dimensions and vertebral shape indices (VSI) were investigat
ed in T4-L4 in 926 females aged 50-81 years. The most consistent findi
ng was the increase of inferior antero-posterior dimension with age. W
edging and concavity also increased with age but the changes were not
significant at all vertebral levels, The value of VSIs also varied wit
h level. Thus a particular degree of VSI, considered normal at one lev
el or at one age, would be outside the reference range at a different
level or age group. The number of subjects identified as osteoporotic
by skewness (5.4%) or in excess of three standard deviations from the
mean (6.5%) was much lower than in recent reports from North America.
The number of subjects contributing to a skewed distribution increased
with age from 0.5% at 55-59 years to 10.0% at 75-79 years. Change wit
h age in the antero-posterior dimension could increase load-bearing ar
ea in older subjects, but the decline in bone density will be increase
d as a declining bone mineral content occupies a larger volume.