Hc. Pape et al., PRIMARY INTRAMEDULLARY FEMUR FIXATION IN MULTIPLE TRAUMA PATIENTS WITH ASSOCIATED LUNG CONTUSION - A CAUSE OF POSTTRAUMATIC ARDS, The journal of trauma, injury, infection, and critical care, 34(4), 1993, pp. 540-548
We investigated whether primary (<24 hours) intramedullary stabilizati
on of femoral shaft fractures in multiple trauma patients with severe
thoracic injury might be associated with an increased incidence of adu
lt respiratory distress syndrome (ARDS). A total of 766 patients with
multiple trauma admitted to Hannover Medical School between January 1,
1982, and December 31, 1991, were investigated retrospectively. Of th
ese, 106 patients met the inclusion criteria: Injury Severity Score >
18, femoral midshaft fracture treated by intramedullary nailing, prima
ry admission or referral within 8 hours after injury, and no death fro
m head injury or hemorrhagic shock. Two groups were differentiated acc
ording to the presence or absence of chest trauma (severe chest trauma
= AIS thorax greater-than-or-equal-to, group T; no severe chest traum
a = AIS thorax < 2, group N). Selection of subgroups according to the
time of femur stabilization was group I < 24 hours after trauma, group
II > 24 hours after trauma. Injury Severity Scores in the four groups
were TI: 29.4 (n = 24); TII 31.4 (n = 26); NI 20.1 (n = 33); NII 25.4
(n = 23). In patients without thoracic trauma the ICU time (NI: 7.3 d
ays; NII: 18.0 days) and intubation time (NI: 5.5 days; NII: 11.0 days
) were lower in the patients treated primarily (p < 0.05). In patients
with severe chest trauma there was a higher incidence of posttraumati
c ARDS (33% versus 7.7%) and mortality (21% versus 4%) when early intr
amedullary femoral nailing was done. In the absence of severe chest tr
auma primary intramedullary femoral nailing is beneficial. In the pres
ence of pulmonary injury primary intramedullary femoral nailing causes
additional pulmonary damage and may trigger ARDS.