BASIC-LANGUAGE SOFTWARE FOR SIMULTANEOUS MONITORING OF BLOOD-GLUCOSE LEVEL AND NEURONAL FIRING FREQUENCY

We have designed software for an Apple II GS microcomputer allowing si multaneous on-line monitoring of blood glucose level and neuronal firi ng frequency in experimental rats. Mood glucose level in the carotid b lood was continuously measured by a glucose analyzer and digitized thr ough an A/D board. The firing rate of a brain neuron, recorded by a cl assical technique, was counted by a versatile interface adapter. Both parameters are graphically displayed on the screen. They can also be e xported to another computer for off-line analysis. This software is ad aptable to other experimental applications in electrophysiology, invol ving the monitoring of glycemia or other biological parameters.