FLUORESCENT DIAGNOSTICS OF HUMAN GASTRIC-CANCER AND SODIUM FLUORESCEIN ACCUMULATION IN EXPERIMENTAL GASTRIC-CANCER IN RATS

Authors
BRAGINSKAJA OV LAZAREV VV POLSACHEV VI RUBIN LB STOSKII VE
Citation
Ov. Braginskaja et al., FLUORESCENT DIAGNOSTICS OF HUMAN GASTRIC-CANCER AND SODIUM FLUORESCEIN ACCUMULATION IN EXPERIMENTAL GASTRIC-CANCER IN RATS, Cancer letters, 69(2), 1993, pp. 117-121
Citations number
12
Categorie Soggetti
Oncology
Journal title
Cancer letters → ACNP
ISSN journal
03043835
Volume
69
Issue
2
Year of publication
1993
Pages
117 - 121
Database
ISI
SICI code
0304-3835(1993)69:2<117:FDOHGA>2.0.ZU;2-B
Abstract
Patients (459) with chronic gastritis, ulcers, polyposis and different types of gastric cancers were examined by endoscopic fluorescent tech nique using a special drug based on the sodium salt of fluorescein (Fl ). Eighty-five percent of gastric cancers showed positive fluorescence . The Fl distribution in the stomach of the rat with induced gastric c ancer was examined. In all cases the level of Fl fluorescence in the t umor was higher than in the adjacent normal tissues of the stomach. Th us, all the obtained results confirm the selective accumulation of Fl in tumors of the stomach.