Five cases are reported of spontaneous remission of chronic childhood
thrombocytopenia four or more years after diagnosis. Other than typica
l features of chronic idiopathic thrombocytopenic purpura there were n
o obvious markers predictive of late remission, although a slow progre
ssive recovery was common to four of the patients. In light of this ex
perience splenectomy is not recommended in clinically mild thrombocyto
penia.