CDPI3-ENEDIYNE AND CDPI3-EDTA CONJUGATES - A NEW CLASS OF DNA CLEAVING AGENTS

Authors
Citation
Dl. Boger et Jc. Zhou, CDPI3-ENEDIYNE AND CDPI3-EDTA CONJUGATES - A NEW CLASS OF DNA CLEAVING AGENTS, Journal of organic chemistry, 58(11), 1993, pp. 3018-3024
Citations number
64
Categorie Soggetti
Chemistry Inorganic & Nuclear
ISSN journal
00223263
Volume
58
Issue
11
Year of publication
1993
Pages
3018 - 3024
Database
ISI
SICI code
0022-3263(1993)58:11<3018:CACC-A>2.0.ZU;2-X
Abstract
The synthesis and preliminary evaluation of la and lb, prototypical CD PI3-enediyne and CDPI3-EDTA conjugates constituting a new class of DNA cleaving agents, are detailed.