NERVOUS-TISSUE PROTEOGLYCANS

The structure, biosynthesis, localization, and possible functional rol es of nervous tissue glycosaminoglycans and proteoglycans were last re viewed several years ago70,74. Since that time, there has been an expo nential increase in publications on the neurobiology of proteoglycans. This review will therefore focus on reports which have appeared in th e period after 1988, and especially on those concerning the properties of individual characterized nervous tissue proteoglycans. Related are as such as the regulation of glycosaminoglycan biosynthesis and the ro les of cell surface proteoglycans in adhesion and growth control are c overed in other contributions to this special topic issue.