Squamous cell carcinoma of the base of tongue is known to have a poor
clinical prognosis that is primarily attributable to such tumors usual
ly presenting at an advanced stage. Fortunately, if detected early, th
ese malignancies may have a more favorable prognosis. We have reviewed
the current literature of squamous cell carcinoma of the base of tong
ue, focusing on epidemiologic data, treatment options, as well as surv
ival results. Data have also been incorporated from a previously unpub
lished retrospective study performed in the Department of Otolaryngolo
gy at the University of Pittsburg.