We report two cases with chronic arsenicism. The first one is a young
37-year-old woman who presents leucomelanoderma, plantar keratoderma,
polyneuropathy of the legs and transversal striae of the nails. After
investigations, criminal intoxication with arsenic caused by her own s
ister was discovered. The second case is a 42-year-old man who had dev
eloped plantar keratoderma, arsenical keratoses and two squamous cell
epitheliomas 10 years after a 2-year treatment with Fowler's solution
for androgenetic alopecia.