A patient is reported in whom neonatal small left colon syndrome (NSLC
S) was present with caecal perforation in conjunction with cystic fibr
osis, presenting as meconium ileus. The pregnancy, in a 36-year-old pr
imigravida, was characterised by alcohol and nicotine abuse but was ot
herwise normal. There was no maternal diabetes. Management by temporar
y bowel diversion, in conjunction with pancreatic enzyme replacement,
was effective.