POLYCYSTIC OVARIAN SYNDROME - EVIDENCE FOR AN AUTOIMMUNE MECHANISM INSOME CASES

Antiovarian autoantibodies localized to the granulosa cells were detec ted in 50% of a group of eight patients diagnosed with polycystic ovar ian syndrome. An analogy is drawn to other endocrinopathies characteri zed by hypersecretion of hormones, notably thyroid and adrenal, and a pathogenetic mechanism involving stimulating antibody is postulated.