C. Bartoloni et al., PSYCHOLOGICAL STATUS, LIFE AND SOCIAL CONDITIONS - A STUDY IN A POPULATION OF INSTITUTIONALIZED ELDERLY PEOPLE, International journal of geriatric psychiatry, 8(5), 1993, pp. 419-426
The relationship between social and life conditions on the one hand an
d the presence of depression on the other was analysed in a population
of institutionalized elderly subjects. The influence of health status
on psychological condition and the presence of endocrinological chang
es in hormones associated with chronic stress were investigated in dep
ressed elderly people: One hundred and thirty-seven elderly people (me
an age 82.4 +/- 7.7) were studied and 60 of them underwent a thorough
psychiatric examination. The overall prevalence of depression-not prev
iously diagnosed in all but one patient-was 76.6%; 23.3% were severely
depressed. Neither gender nor the presence of organic disease differe
ntiated the depressed from the non-depressed. The only two life and so
cial variables associated with depression among the many items analyse
d were the length of institutionalization and the period of retirement
. It was observed that a higher cortisol level in the severely depress
ed group showed a positive correlation between plasma (and urine) cort
isol level and Hamilton Rating Scale for Depression (HRSD) score. A re
lationship between immunological impairment and depression in old age
has been reported elsewhere; it is suggested that these findings could
be partly mediated by the observed endocrinological changes.