Fucidic acid viscous eye drops 1% given twice daily was compared with
chloramphenicol eye drops 0.5% given 6 times daily in patients with ac
ute conjunctivitis. Patients were recruited from 38 general practition
ers in Norway. The mean duration of treatment was 6.6 days for Fucidic
acid, 6.2 days for chloramphenicol. There was no major differences be
tween the two groups in the bacteriological findings, and there was no
significant difference in response to treatment. The use of fusidic a
cid in a carbomer vehicle as in Fucithalmic, has proved to give a long
-lasting antibiotic concentration in the tear fluid, which allows the
preferable twice daily application.