Orosomucoid levels were measured in the seminal plasma of 185 men divi
ded in a) twelve groups according to etiological diagnosis of infertil
ity and b) two groups on the basis of the normal or abnormal spermiogr
am. There was no significant difference of the concentration of semina
l plasma orosomucoid between the controls and the patients of the othe
r groups. There was no correlation between seminal plasma orosomucoid
concentration and sperm concentration, as well as between seminal plas
ma orosomucoid level and sperm motility. The evaluation of orosomucoid
in the seminal plasma is not of diagnostic value in the workup of mal
e infertility.