COLLISION-INDUCED DISSOCIATIONS OF DEPROTONATED PEPTIDES - DIPEPTIDESCONTAINING ASN, ARG AND LYS

Authors
WAUGH RJ BOWIE JH GROSS ML
Citation
Rj. Waugh et al., COLLISION-INDUCED DISSOCIATIONS OF DEPROTONATED PEPTIDES - DIPEPTIDESCONTAINING ASN, ARG AND LYS, Australian Journal of Chemistry, 46(5), 1993, pp. 693-702
Citations number
22
Categorie Soggetti
Chemistry
Journal title
Australian Journal of Chemistry → ACNP
ISSN journal
00049425
Volume
46
Issue
5
Year of publication
1993
Pages
693 - 702
Database
ISI
SICI code
0004-9425(1993)46:5<693:CDODP->2.0.ZU;2-T
Abstract
The presence and position of Asn, Arg and Lys residues in dipeptides m ay be determined from a consideration of the collisional activation ma ss spectra of the (M - H)- ions formed by fast atom bombardment. All s pectra show the basic dipeptide cleavage, i.e. NH2CH(R1)CONHCH(R2)CO2- --> NH2CBAR(R1)CONHCH(R2)CO2H --> NH2C(R1)=C=O + -NHCH(R2)CO2H. There are a number of fragmentations characteristic of a particular alpha s ide chain: for example, Arg loses HN=C=NH (42 u).