A self-expanding esophageal nitinol stent was implanted under fluorosc
opic guidance in 40 patients with malignant esophageal strictures and
clinically significant dysphagia. The strictures were caused by squamo
us cell carcinoma (n = 14), adenocarcinoma (n = 12), recurrent anastom
otic carcinoma (n = 8), and mediastinal tumors (n = 6). Eight stents w
ere balloon dilated to maximum diameter immediately after insertion. S
ixteen stents self-expanded to maximum diameter within 24 hours, and t
he other stents expanded to maximum diameter during further observatio
n. There were no serious stent-related complications, and the dysphagi
a was reduced considerably in all patients immediately after stent ins
ertion. Persistent tumor bleeding occurred in two patients, and ingrow
th of tumor into the stent was seen in eight patients. Two stents occl
uded due to tumor ingrowth but were successfully recanalized with endo
scopic laser coagulation. At the end of the study, 28 patients were de
ad with a mean survival of 2.9 months (range, 0.1-7.0 months), and 12
patients were alive with a mean follow-up of 8.8 months (range, 4.0-15
.0 months).