AMINO-ACIDS AND PEPTIDES .18. SYNTHETIC PEPTIDES RELATED TO N-TERMINAL PORTION OF FIBRIN ALPHA-CHAIN AND THEIR INHIBITORY EFFECT ON FIBRINOGEN THROMBIN CLOTTING

Authors
KAWASAKI K MIYANO M HIRASE K IWAMOTO M
Citation
K. Kawasaki et al., AMINO-ACIDS AND PEPTIDES .18. SYNTHETIC PEPTIDES RELATED TO N-TERMINAL PORTION OF FIBRIN ALPHA-CHAIN AND THEIR INHIBITORY EFFECT ON FIBRINOGEN THROMBIN CLOTTING, Chemical and Pharmaceutical Bulletin, 41(5), 1993, pp. 975-977
Citations number
14
Categorie Soggetti
Pharmacology & Pharmacy",Chemistry
Journal title
Chemical and Pharmaceutical Bulletin → ACNP
ISSN journal
00092363
Volume
41
Issue
5
Year of publication
1993
Pages
975 - 977
Database
ISI
SICI code
0009-2363(1993)41:5<975:AAP.SP>2.0.ZU;2-3
Abstract
Peptide analogs of the N-terminal portion of fibrin alpha-chain were p repared and their inhibitory effects on fibrinogen/thrombin clotting w ere examined. Of the synthetic peptides, H-Cly-Pro-Arg-Pro-Pro-NH2 exh ibited the most potent inhibitory effect.