Sd. Hillis et al., DELAYED CARE OF PELVIC INFLAMMATORY DISEASE AS A RISK FACTOR FOR IMPAIRED FERTILITY, American journal of obstetrics and gynecology, 168(5), 1993, pp. 1503-1509
OBJECTIVE: We evaluated the relationship between delayed care of sympt
omatic pelvic inflammatory disease and impaired fertility. STUDY DESIG
N: We used data from a cohort of women with clinically recognized pelv
ic inflammatory disease. Case patients were women with either ectopic
pregnancy or infertility (n = 76); controls were women with intrauteri
ne pregnancies (n = 367). RESULTS: Women who delayed seeking care for
pelvic inflammatory disease were three times more likely to experience
infertility or ectopic pregnancy than women who sought care promptly
after adjustment for age, organism, year of diagnosis, and history of
recent gynecologic events (95% confidence interval = 1.27, 6.11). This
association was strongest for women with chlamydia; 17.8% (18/101) of
those who delayed seeking care had impaired fertility, whereas 0.0% (
0/13) of those who sought care promptly suffered known sequelae. CONCL
USIONS: Women with pelvic inflammatory disease who delay seeking care
are at increased risk for infertility and ectopic pregnancy. Furthermo
re, our data suggest that prompt evaluation and treatment of chlamydia
l pelvic inflammatory disease can prevent these sequelae.