A NEW BIOACTIVE BONE-CEMENT CONSISTING OF BIS-GMA RESIN AND BIOACTIVEGLASS POWDER

We have developed a bioactive bone cement consisting of silane-treated CaO-SiO2-P2O5-CaF2 glass powder as the filling particles and bispheno l-a-glycidyl methacrylate (BIS-GMA) diluted with triethylene-glycol di methacrylate (TEGDMA) as the organic matrix. Histological examination demonstrated direct bonding between the cement and bone along the circ umference of the cement at 4 weeks after implantation in rat tibia. Th e compressive strength and toughness of the cement were two and four t imes greater than those of polymethylmethacrylate (PMMA) cement, respe ctively. The inflammatory reaction of the skin caused by the new cemen t was not as intense as that for PMMA 3 days after subcutaneous implan tation. This new cement may be applicable as a bioactive bone cement w ith high mechanical strength.