Ej. Margalioth et al., CORRELATIONS BETWEEN SERUM ESTRADIOL LEVEL ON DAY OF HCG AND SPEED OFEMBRYONIC-DEVELOPMENT IN INVITRO FERTILIZATION, Human reproduction, 8(5), 1993, pp. 752-754
The number of embryos transferred, ease of embryo transfer, and rate o
f embryo cleavage are significant factors affecting the success of IVF
. High levels of oestradiol occurring when HCG is given may reduce imp
lantation and pregnancy rates. A discrepancy between the stage of embr
yonic development and the phase of endometrial maturation at embryo tr
ansfer may be responsible for IVF failure in some cases.