BIOPSY-PROVEN ISOLATED SARCOID MENINGITIS - CASE-REPORT

Neurosarcoidosis without systemic involvement is rare and difficult to diagnose. The case of a 27-year-old man with a 6-week history of head ache, mental status changes, and polyradiculopathy attributable to hyp oglycorrheic lymphocytic meningitis is presented. Extensive testing fo r occult systemic sarcoidosis was negative. The presence of noncaseati ng granulomatous inflammation was established by open brain biopsy, an d the patient improved clinically with oral steroid therapy. In indivi duals with undiagnosed chronic meningitis, brain biopsy may be necessa ry to rule out isolated neurosarcoidosis.