Two cases of ipecac myopathy, one with associated cardiomyopathy are r
eported. Both patients were young women with eating disorders who came
to medical attention because of diffuse muscle weakness. Clinical and
electromyographic data suggested ipecac myopathy and muscle biopsies
confirmed this diagnosis. One patient had associated clinical and echo
cardiographic evidence of significant cardiomyopathy. The myopathy res
olved and the echocardiogram returned to normal after discontinuing th
e use of ipecac.