CHARACTERIZATION OF CAPACITATION INHIBITORY PROTEIN FROM RABBIT SEMINAL PLASMA - HOMOLOGY WITH HUMAN ANNEXINS

Authors
OKABE M KISHI Y YING X KOHAMA Y MIMURA T LI SSL
Citation
M. Okabe et al., CHARACTERIZATION OF CAPACITATION INHIBITORY PROTEIN FROM RABBIT SEMINAL PLASMA - HOMOLOGY WITH HUMAN ANNEXINS, Biological & pharmaceutical bulletin, 16(5), 1993, pp. 453-456
Citations number
31
Categorie Soggetti
Pharmacology & Pharmacy
Journal title
Biological & pharmaceutical bulletin → ACNP
ISSN journal
09186158
Volume
16
Issue
5
Year of publication
1993
Pages
453 - 456
Database
ISI
SICI code
0918-6158(1993)16:5<453:COCIPF>2.0.ZU;2-2
Abstract
A protein was purified from rabbit seminal plasma using preparative ac rylamide disc electrophoresis, ammonium sulfate precipitation and gel filtration. The protein inhibited the in vitro fertilization of mouse ova inseminated with epididymal sperm and with capacitated sperm. The inhibition was not observed, however, when only ova were exposed to th e protein prior to mixing with sperm. The partial protein sequence ana lysis revealed the strong homology of the rabbit fertilization inhibit ory protein to human annexin V.