INVITRO TESTS OF NEUROTOXICITY

This review presents some of the newer techniques in the rapidly advan cing area of neurotoxicity testing in vitro. They are not described at length, and more details can be obtained from the cited references. I n vitro testing offers the possibility of relatively inexpensive scree ning of large numbers of pharmaceutical compounds, formulations, and e nvironmental substances. The level of sophistication attained in this field may soon allow much more accurate safety limits to be set, as sp ecific mechanisms of neurotoxicity are elucidated.