Radiologists and pathologists play the most important role in the diag
nosis of breast diseases. The combination of mammographic and cytologi
cal investigations can lead to the determination of which lesions requ
ire an operation and which do not. Fibroadenomas, mastopathies and car
cinomas are the most common histological diagnoses. It is necessary to
decide which type of mastopathy (atypical intraductal or intralobular
hyperplasia) might involve a higher risk of carcinoma. When classifyi
ng carcinomas, the pathologist must give details about prognostic fact
ors such as staging (pTN status), histological typing, grading, and ho
rmone receptors (oestrogen and gestagen).