Conservative therapeutic concepts with initial chemotherapy for patien
ts with breast cancer represent a challenge to non-invasive techniques
for monitoring response to therapy. Experimental magnetic resonance s
pectroscopy studies have been able to show exemplary applications for
therapy monitoring of breast cancer patients. The characteristic phosp
homonoester resonances and their changes during therapy are possible c
linical parameters. The additional information which can be obtained f
rom proton and carbon spectroscopy increases the amount of detectable
metabolites. On-going studies are investigating clinical applications
of multinuclear spectroscopic studies in patients with breast cancer.