AN ENANTIOSELECTIVE APPROACH TO THE SYNTHESIS OF POLYCYCLIC ETHERS

Authors
MARTIN VS ODE JM PADRON JM PALAZON JM RAMIREZ MA SOLER MA
Citation
Vs. Martin et al., AN ENANTIOSELECTIVE APPROACH TO THE SYNTHESIS OF POLYCYCLIC ETHERS, Anales de quimica, 89(1), 1993, pp. 67-72
Citations number
30
Categorie Soggetti
Chemistry
Journal title
Anales de quimica → ACNP
ISSN journal
11302283
Volume
89
Issue
1
Year of publication
1993
Pages
67 - 72
Database
ISI
SICI code
1130-2283(1993)89:1<67:AEATTS>2.0.ZU;2-S
Abstract
The enantiomeric synthesis by intramolecular hetero-Michael additions of polysubstituted and polycyclic ethers present in marine toxins is d escribed. The stereoselectivity in the cyclization steps is governed b y the double bond geometry of the electrophylic double bond. A silicon assistance observed in the cyclization step led to the stereocontroll ed synthesis of oxepanes.