G. Borgnolo et al., LOUSE-BORNE RELAPSING FEVER - A CLINICAL AND AN EPIDEMIOLOGIC-STUDY OF 389 PATIENTS IN ASELLA-HOSPITAL, ETHIOPIA, Tropical and geographical medicine, 45(2), 1993, pp. 66-69
An outbreak of louse-borne relapsing fever, due to the return of soldi
ers to their original recruitment areas, after the end of thirty years
of fighting in northern Ethiopia, was reported in Arsi region, southe
rn Ethiopia. The epidemic spread to different members of the community
and eventually the schools. We studied 389 patients affected by the e
pidemic and who were admitted to Asella Hospital between June 1991 and
May 1992. Twenty-seven per cent of the patients were ex-soldiers; 28%
were students, who were admitted to the hospital since the schools we
re opened after the summer vacations. The common clinical features of
the disease were fever (99%), headache (92%), hepatosplenomegaly (66%)
, myalgia (55%), arthralgia (51%), petechial rash (43%), epistaxis (24
%) and jaundice (23%). Observed complications were pneumonia (10%), pu
lmonary edema (6%), myocarditis (3%) and 6 abortions in 15 pregnancies
. Patients were treated with low dose penicillin anti I.V. fluids. The
in-hospital case fatality rate was 3.6%. Jarisch-Herxheimer reaction
occurred in 43% of the patients. 1.8% of the patients had relapses aft
er treatment.