Numerous studies report that water fluoridation reduces caries in chil
dren, but little current evidence exists about fluoridation's effects
on the periodontal health of adults. To address this issue, we estimat
ed fluoridation effects on periodontal disease among 1066 Washington s
tate employees and their spouses, aged 20 to 34, with current residenc
es divided evenly between fluoridated and nonfluoridated communities.
Subjects were interviewed by telephone to collect residence histories,
personal characteristics and other data. Each subject's lifetime year
s of fluoridation exposure (YFE) was calculated from the person's resi
dence history and the U.S. Centers for Disease Control's Fluoridation
Census. Oral assessments were conducted to measure the extent of perio
dontal disease. Relative to adults with no exposure, continuous lifeti
me exposure reduced the probability of attachment loss from 0.87 to 0.
72. Similar benefits were obtained for bleeding gingiva and calculus.
The estimates of fluoridation's benefits were not influenced by select
ion bias due to subjects' nonparticipation in the oral assessments.