SARAFOTOXINS AND ENDOTHELINS - EVOLUTION, STRUCTURE AND FUNCTION

Authors
KOCHVA E BDOLAH A WOLLBERG Z
Citation
E. Kochva et al., SARAFOTOXINS AND ENDOTHELINS - EVOLUTION, STRUCTURE AND FUNCTION, Toxicon, 31(5), 1993, pp. 541-568
Citations number
151
Categorie Soggetti
Toxicology,"Pharmacology & Pharmacy
Journal title
Toxicon → ACNP
ISSN journal
00410101
Volume
31
Issue
5
Year of publication
1993
Pages
541 - 568
Database
ISI
SICI code
0041-0101(1993)31:5<541:SAE-ES>2.0.ZU;2-W
Abstract
The venom of the burrowing asp Atractaspis engaddensis contains severa l 21 amino acid residue peptides known as sarafotoxins. The sarafotoxi ns are homologous to the mammalian endothelin family, and they have si milar biological activities. This review covers recent advances in the study of the chemical and biological properties of the sarafotoxins a nd endothelins.