We recently encountered a case of recurrent non-Hodgkin's lymphoma man
ifested after a long period of quiescence as bilateral involvement of
the breasts, This 37-year-old woman had stage IVA nodular poorly diffe
rentiated lymphocytic lymphoma diagnosed 9 years previously and was fo
llowed up without treatment, She was lost to follow-up after 4 years b
ut had been in good health until seen with malaise and fever and pain,
swelling, and erythema involving both breasts, Biopsies of lymph node
and bone marrow showed a high-grade non-Hodgkin's lymphoma (lymphobla
stic lymphoma) of B cell origin with central nervous system involvemen
t, Combination chemotherapy produced a dramatic remission, but the pat
ient died of Pseudomonas septicemia.