A restrospective review of 2,216 patients surgically treated for a cli
nical diagnosis of acute appendicitis was performed. In 80% of cases,
histologic acute appendictitis was found; 57% of these patients were m
ale. The rate of normal appendectomy was 16%, and females comprised 68
% of that group. The remaining 102 cases (4%) were designated as the a
lternate diagnosis group. Apart from histologic diagnoses that could b
e considered variants of normal (57) or acute inflammation (20), the a
lternate diagnosis group included such entities as neoplasm, parasitic
infection, mucocele, and diverticulitis.