We examined 3 patients with isolated retinal macroaneurysms and second
ary hemorrhage by standard fluorescein angiography (FA) and indocyanin
e green (ICG) angiography. In contrast to standard FA, ICG videoangiog
raphy clearly demonstrated the lesion to be pulsatile, contiguous with
the arterial wall and pathognomonic of an isolated retinal artery mac
roaneurysm ICG with its absorption and emission peak in the near-infra
red range penetrates hemorrhage to a greater degree than does blue or
green light of conventional FA. ICG can be essential in delineating th
e specific cause of the bleeding and allow the physician to choose the
correct specific form of treatment needed.