APPLICATION OF SURFACE ELECTROMAGNETIC-WAVE AND SURFACE-PLASMON TECHNIQUES IN A PROTEIN ADSORPTION STUDY AND SENSOR CONSTRUCTION

Authors
SILIN VI BALCYTIS GA ZHIZHIN GN YAKOVLEV VA
Citation
Vi. Silin et al., APPLICATION OF SURFACE ELECTROMAGNETIC-WAVE AND SURFACE-PLASMON TECHNIQUES IN A PROTEIN ADSORPTION STUDY AND SENSOR CONSTRUCTION, Vibrational spectroscopy, 5(1), 1993, pp. 133-142
Citations number
23
Categorie Soggetti
Spectroscopy,"Chemistry Analytical","Chemistry Physical
Journal title
Vibrational spectroscopy → ACNP
ISSN journal
09242031
Volume
5
Issue
1
Year of publication
1993
Pages
133 - 142
Database
ISI
SICI code
0924-2031(1993)5:1<133:AOSEAS>2.0.ZU;2-T
Abstract
Protein adsorption on aluminium, copper and modified silver film surfa ces was investigated by surface electromagnetic wave (SEW) and surface plasmon (SP) techniques. The application of SEW and SP methods in mod elling and real systems (human blood serum) is considered for immuno-t ype biosensor construction. The influence of surface roughness and mul ti-layer formation technology on the sensitivity of these methods is d iscussed. An experimental sensitivity of 5 x 10(-6) Mg ml-1 ferritin i n a real system was obtained with an SP-based biosensor.