The resazurin reduction test was performed on semen samples from 83 un
treated infertile and 9 pregnancy-confirmed fertile males, and the res
ults were compared with other sperm parameters. The highest correlatio
ns with resazurin grade were found for motile sperm concentration (r=0
.65, P<0.001), percent motility (r=0.58, P<0.01), and percentage of sw
ollen sperm (r=0.57, P<0.01). There were also significant but weak cor
relations between resazurin grade and both sperm concentration and lin
earity. There was a significant difference in the rate of positive tes
ts between samples from normozoospermic and fertile males, and samples
from patients exhibiting abnormal semen parameters (P<0.001). These f
indings indicate that the resazurin test may be able to predict those
males who may be fertile despite an abnormal semen analysis, and there
fore, the test may be useful in the evaluation of the infertile patien
t as a part of a comprehensive male fertility assessment.