The nucleotide sequence of the Candida albicans erg7 gene, which compl
ements erg7 mutants of Saccharomyces cerevisiae and restores oxidosqua
lene cyclase activity, was determined. The gene encodes a 728-aa prote
in that displays homology with squalene-hopene cyclase, providing furt
her evidence that erg7 is the gene encoding 2,3-oxidosqualene cyclase.