This literature review compares the efficacy of the two most commonly
recommended bedside tests for detecting aspiration in tube-fed patient
s: (1) adding dye to the formula and observing for its appearance in t
racheobronchial secretions, and (2) using glucose oxidase reagent stri
ps to test tracheobronchial secretions for glucose-containing enteral
formula. The review also describes potential problems and cost associa
ted with each test. Several studies indicate that the dye method is fa
r less sensitive than the glucose reagent method; further, there are a
necdotal reports of potential harm to patients when dye is added to tu
be feedings. Specificity of the glucose method has been challenged by
several authors; also, cost is probably greater with this method.