Ss. Ginsberg et al., SUCCESSFUL CHILDBIRTH BY A PATIENT WITH CONGENITAL FACTOR-XI DEFICIENCY AND AN ACQUIRED INHIBITOR, British Journal of Haematology, 84(1), 1993, pp. 172-174
Acquired inhibitors in factor XI deficiency (FXI) are rare. The presen
ce of an inhibitor during pregnancy poses a potential haemorrhagic ris
k to the fetus. We report an uncomplicated pregnancy and successful ch
ildbirth by a woman with congenital FXI deficiency and an acquired inh
ibitor, and discuss the persistence of residual FXI activity in the pr
esence of an inhibitor.