IDENTIFICATION OF GALEGINE, AN ISOPRENYL GUANIDINE, AS THE TOXIC PRINCIPLE OF SCHOENUS-ASPEROCARPUS (POISON SEDGE)

Authors
HUXTABLE CR DORLING PR COLEGATE SM
Citation
Cr. Huxtable et al., IDENTIFICATION OF GALEGINE, AN ISOPRENYL GUANIDINE, AS THE TOXIC PRINCIPLE OF SCHOENUS-ASPEROCARPUS (POISON SEDGE), Australian Veterinary Journal, 70(5), 1993, pp. 169-171
Citations number
9
Categorie Soggetti
Veterinary Sciences
Journal title
Australian Veterinary Journal → ACNP
ISSN journal
00050423
Volume
70
Issue
5
Year of publication
1993
Pages
169 - 171
Database
ISI
SICI code
0005-0423(1993)70:5<169:IOGAIG>2.0.ZU;2-V
Abstract
An isoprenyl guanidine, galegine, was isolated from the Western Austra lian sedge Schoenus asperocarpus (Cyperaceae). Synthetic galegine was shown to reproduce the clinical and pathological features of poisoning by this plant. Preliminary results suggest that the massive thoracic effusion observed in sedge poisoning is the result of a direct effect on pulmonary vascular permeability.