TREATMENT OF STAGE-I TESTICULAR-TUMORS

Citation
Jrg. Lluch et al., TREATMENT OF STAGE-I TESTICULAR-TUMORS, British Journal of Urology, 71(4), 1993, pp. 473-477
Citations number
26
Categorie Soggetti
Urology & Nephrology
Journal title
ISSN journal
00071331
Volume
71
Issue
4
Year of publication
1993
Pages
473 - 477
Database
ISI
SICI code
0007-1331(1993)71:4<473:TOST>2.0.ZU;2-8
Abstract
Between 1980 and 1989, 138 patients with stage I carcinoma of the test es were treated and followed up; 81 patients had seminoma and 57 had n on-seminomatous tumours. Between January 1980 and December 1983, patie nts with seminoma were treated by orchiectomy, followed by complementa ry radiotherapy to aortic and ipsilateral pelvic nodes. Retroperitonea l lymph node dissection (RPLND) was performed in patients with non-sem inomatous tumours. After January 1984 the treatment strategy was chang ed and orchiectomy was followed by a surveillance policy in all histol ogical types. In seminoma patients, 1 of 36 patients (3%) treated with complementary radiotherapy and 5 of 45 (11%) on the surveillance poli cy relapsed. All achieved a complete response after chemotherapy. In n on-seminomatous tumours, 3 of 21 patients (14%) treated with complemen tary lymphadenectomy relapsed, in contrast to 11 of 36 (31%) surveilla nce policy patients. All patients who relapsed obtained a complete res ponse with chemotherapy. All patients are currently free of disease. T here were no differences in survival between both treatment policies. We conclude that a wait and see policy in stage I testicular tumours i s feasible and provides the same results as more interventionist pract ices.