ON STEROIDS .366. PREPARATION OF UNLABELED AND [H-3] LABELED EPITESTOSTERONE AND ITS METABOLITES

Authors
KASAL A FUKSOVA K POUZAR V
Citation
A. Kasal et al., ON STEROIDS .366. PREPARATION OF UNLABELED AND [H-3] LABELED EPITESTOSTERONE AND ITS METABOLITES, Collection of Czechoslovak Chemical Communications, 58(3), 1993, pp. 600-611
Citations number
38
Categorie Soggetti
Chemistry
Journal title
Collection of Czechoslovak Chemical Communications → ACNP
ISSN journal
00100765
Volume
58
Issue
3
Year of publication
1993
Pages
600 - 611
Database
ISI
SICI code
0010-0765(1993)58:3<600:OS.POU>2.0.ZU;2-U
Abstract
Cold as well as [H-3]-labelled substrates and metabolites IX - XI, XV, XVI, XX - XXII, XXIV, XXV and XXVIII were prepared by catalytic hydro genation of epitestosterone (VIII) and LAMBDA1-dehydroepitestosterone (XIII). The key step in the preparation of compound XXVIII was reactio n of 3beta-tosylates XXVI and XXX with potassium nitrite in dimethyl s ulfoxide.