PREPARATION OF POLYFUNCTIONAL PHOSPHINES USING ZINC ORGANOMETALLICS

Authors
LANGER F PUNTENER K STURMER R KNOCHEL P
Citation
F. Langer et al., PREPARATION OF POLYFUNCTIONAL PHOSPHINES USING ZINC ORGANOMETALLICS, Tetrahedron : asymmetry, 8(5), 1997, pp. 715-738
Citations number
53
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Inorganic & Nuclear","Chemistry Physical
Journal title
Tetrahedron : asymmetry → ACNP
ISSN journal
09574166
Volume
8
Issue
5
Year of publication
1997
Pages
715 - 738
Database
ISI
SICI code
0957-4166(1997)8:5<715:POPPUZ>2.0.ZU;2-6
Abstract
The reaction of functionalized diorganozincs with chlorodiorganophosph ines provides polyfunctional phosphines in good yields. Especially att ractive is the hydroboration/boron-zinc exchange sequence which allows the conversion of functionalized olefins into polyfunctional phosphin es in a one-pot procedure. Several new chiral phosphines have been pre pared starting from readily available chiral olefins (terpenes) and th eir efficiency in asymmetric hydrogenation reactions has been evaluate d. (C) 1997 Elsevier Science Ltd.