SYNTHESIS AND ENANTIOMERIC EXCESS DETERMINATION OF -6-(N-METHYL-N-BENZYLOXYCARBONYLAMINO)-CYCLOHEXENE

Authors
PECUNIOSO A MAFFEIS M MARCHIORO C ROSSI L TAMBURINI B
Citation
A. Pecunioso et al., SYNTHESIS AND ENANTIOMERIC EXCESS DETERMINATION OF -6-(N-METHYL-N-BENZYLOXYCARBONYLAMINO)-CYCLOHEXENE, Tetrahedron : asymmetry, 8(5), 1997, pp. 775-778
Citations number
11
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Inorganic & Nuclear","Chemistry Physical
Journal title
Tetrahedron : asymmetry → ACNP
ISSN journal
09574166
Volume
8
Issue
5
Year of publication
1997
Pages
775 - 778
Database
ISI
SICI code
0957-4166(1997)8:5<775:SAEEDO>2.0.ZU;2-A
Abstract
The title compound was obtained with high regioisomeric and enantiomer ic purity starting from the tartrate salt of (1S,2S)-1-hydroxy-2-methy laminocyclohexane. The determination of the enantiomeric excess both o f the title compound and of its precursor 2-(N-methyl-N-benzyloxycarbo nylamino)cyclohexanone was determined by NMR experiments with chiral s hift reagents. (C) 1997 Elsevier Science Ltd.